Genes & Proteins (Cambridge (CIE) IGCSE Biology)
Revision Note
Written by: Lára Marie McIvor
Reviewed by: Lucy Kirkham
DNA Base Sequence To Amino Acid Sequence: Extended
The DNA Base Sequence Determines the Amino Acid Sequence in Protein
The DNA code (a series of bases) is converted into proteins (a series of amino acids)
The process of protein synthesis has two stages
Transcription (rewriting the base code of DNA into bases of RNA)
Translation (using RNA base sequence to build amino acids into sequence in a protein)
Therefore, the sequence of bases in a gene determines the sequence of amino acids that make a specific protein
Different sequences of amino acids give different shapes and functions to protein molecules
Examiner Tips and Tricks
Students often confuse sequences of bases (in DNA/RNA) with sequences of amino acids (in proteins).
Make sure you're clear which large molecule you're referring to and therefore, which monomers make up the larger molecule.
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