Genes & Proteins (Cambridge (CIE) IGCSE Biology)

Revision Note

Lára Marie McIvor

Written by: Lára Marie McIvor

Reviewed by: Lucy Kirkham

DNA Base Sequence To Amino Acid Sequence: Extended

The DNA Base Sequence Determines the Amino Acid Sequence in Protein

  • The DNA code (a series of bases) is converted into proteins (a series of amino acids)

  • The process of protein synthesis has two stages

    • Transcription (rewriting the base code of DNA into bases of RNA)

    • Translation (using RNA base sequence to build amino acids into sequence in a protein)

  • Therefore, the sequence of bases in a gene determines the sequence of amino acids that make a specific protein

  • Different sequences of amino acids give different shapes and functions to protein molecules

Examiner Tips and Tricks

Students often confuse sequences of bases (in DNA/RNA) with sequences of amino acids (in proteins).

Make sure you're clear which large molecule you're referring to and therefore, which monomers make up the larger molecule. 

Last updated:

You've read 0 of your 5 free revision notes this week

Sign up now. It’s free!

Join the 100,000+ Students that ❤️ Save My Exams

the (exam) results speak for themselves:

Did this page help you?

Lára Marie McIvor

Author: Lára Marie McIvor

Expertise: Biology Lead

Lára graduated from Oxford University in Biological Sciences and has now been a science tutor working in the UK for several years. Lára has a particular interest in the area of infectious disease and epidemiology, and enjoys creating original educational materials that develop confidence and facilitate learning.

Lucy Kirkham

Author: Lucy Kirkham

Expertise: Head of STEM

Lucy has been a passionate Maths teacher for over 12 years, teaching maths across the UK and abroad helping to engage, interest and develop confidence in the subject at all levels.Working as a Head of Department and then Director of Maths, Lucy has advised schools and academy trusts in both Scotland and the East Midlands, where her role was to support and coach teachers to improve Maths teaching for all.