Genes & Proteins (Cambridge (CIE) IGCSE Biology)

Revision Note

Lára Marie McIvor

Expertise

Biology Lead

DNA Base Sequence To Amino Acid Sequence: Extended

The DNA Base Sequence Determines the Amino Acid Sequence in Protein

  • The DNA code (a series of bases) is converted into proteins (a series of amino acids)

  • The process of protein synthesis has two stages

    • Transcription (rewriting the base code of DNA into bases of RNA)

    • Translation (using RNA base sequence to build amino acids into sequence in a protein)

  • Therefore, the sequence of bases in a gene determines the sequence of amino acids that make a specific protein

  • Different sequences of amino acids give different shapes and functions to protein molecules

Examiner Tip

Students often confuse sequences of bases (in DNA/RNA) with sequences of amino acids (in proteins).

Make sure you're clear which large molecule you're referring to and therefore, which monomers make up the larger molecule. 

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Lára Marie McIvor

Author: Lára Marie McIvor

Lára graduated from Oxford University in Biological Sciences and has now been a science tutor working in the UK for several years. Lára has a particular interest in the area of infectious disease and epidemiology, and enjoys creating original educational materials that develop confidence and facilitate learning.