Mitosis & the Cell Cycle (OCR GCSE Biology A (Gateway))
Revision Note
The Cell Cycle
The cell cycle can be thought of as the life cycle of a cell
It is the series of growth and development steps a cell undergoes
From its formation to the point it divides to make new cells
The cells in your body need to be able to divide to help your body grow and repair itself
Cells grow and divide over and over again
For this to happen the DNA has to be copied
All body cells (except gametes) are produced by mitosis which happens as part of the cell cycle
There are 3 parts of the cell cycle
Interphase - consists of phases of cell growth and synthesis of new DNA
Just before mitosis, the DNA in the nucleus copies itself exactly (forming duplicate chromosomes)
Mitosis - Chromosomes line up along the centre of the cell and are pulled apart
Cytokinesis - The cell cytoplasm and membrane divides to produce two daughter cells
Each new cell has a copy of each of the chromosomes
The three stages of the cell cycle
Mitosis
The process of mitosis is itself made up of a series of stages that begin after interphase has occurred
DNA was copied during interphase to produce duplicate chromosomes
During mitosis, the sets of duplicated chromosomes line-up in the centre of the cell
Cell fibres attach to the duplicated chromosomes and pull them apart
One chromosome arm (chromatid) from each set is pulled to each end of the cell
A new nucleus forms around each group of chromosomes
After this, the cytoplasm and cell membranes divide in a process known as cytokinesis. This results in the formation of two genetically identical daughter cells
Diagram showing the process of cell division by mitosis
Examiner Tips and Tricks
You do need to appreciate the three overall stages of the cell cycle:
Growth phase (including chromosome doubling)
Mitosis
Cytokinesis (division of cytoplasm and the cell membrane)
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