HIV & the Immune System (Cambridge O Level Biology)

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HIV & the Immune System

  • The HIV virus infects a certain type of lymphocyte in the immune system
  • Normally lymphocytes seek out and destroy pathogens that enter the body, producing antibodies that attach to pathogens, enhancing phagocytic activity
  • However, HIV infects a certain type of lymphocyte and uses the cells’ machinery to multiply
  • This reduces the number of lymphocytes in the immune system, and also the number of antibodies that can be made
  • This decreases the body’s ability to fight off infections, eventually leading to AIDS (Acquired immunodeficiency Syndrome)
  • The weakened immune system is susceptible to infections that would normally have been dealt with by a fully-functioning immune system
    • e.g influenza, pneumonia, skin cancer

Examiner Tip

This page focuses on HIV and the immune system, but for more detail on the HIV virus and its effects, see topic 12.1 Human Immunodeficiency Virus

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Phil

Author: Phil

Expertise: Biology

Phil has a BSc in Biochemistry from the University of Birmingham, followed by an MBA from Manchester Business School. He has 15 years of teaching and tutoring experience, teaching Biology in schools before becoming director of a growing tuition agency. He has also examined Biology for one of the leading UK exam boards. Phil has a particular passion for empowering students to overcome their fear of numbers in a scientific context.