Chromosome: GCSE Biology Definition

Ruth Brindle

Written by: Ruth Brindle

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What is a chromosome?

In GCSE biology, a chromosome is a molecule found in the nucleus of a cell which contains genetic information in the form of DNA. Each chromosome carries multiple genes, short sections of the genetic code that contain instructions for building proteins. Chromosomes are passed from parent to offspring, allowing characteristics to be inherited.

Diagram illustrating DNA structure: double helix, DNA strand, chromosome, and nucleus containing chromosomes within a cell. Labels explain each part.
Chromosomes are molecules in the nucleus that contain DNA

In humans, each body cell contains 23 pairs of chromosomes, giving a total chromosome number of 46; human cells containing 46 chromosomes are said to be diploid. Sex cells in humans (egg cells and sperm cells) have a chromosome number of 23, and are described as haploid.

Chromosomes become visible only during cell division. The DNA is replicated, at which point the chromosomes take on a characteristic ‘X’ shape before being allocated to new daughter cells.

Chromosome revision resources to ace your exams

You can explore chromosomes further using our GCSE revision notes, topic questions and flashcards for your specific exam board:

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Ruth Brindle

Author: Ruth Brindle

Expertise: Biology

Ruth graduated from Sheffield University with a degree in Biology and went on to teach Science in London whilst also completing an MA in innovation in Education. With 10 years of teaching experience across the 3 key science disciplines, Ruth decided to set up a tutoring business to support students in her local area. Ruth has worked with several exam boards and loves to use her experience to produce educational materials which make the mark schemes accessible to all students.

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