Enzymes (Cambridge (CIE) IGCSE Biology): Revision Note

Exam code: 0610 & 0970

Lára Marie McIvor

Written by: Lára Marie McIvor

Reviewed by: Jenna Quinn

Updated on

What are enzymes?

  • Enzymes are:

    • catalysts that speed up the rate of a chemical reaction without being changed or used up in the reaction

    • proteins

    • biological catalysts (biological because they are made in living cells, catalysts because they speed up the rate of chemical reactions without being changed)

    • necessary to all living organisms as they maintain reaction speeds of all metabolic reactions (all the reactions that keep an organism alive) at a rate that can sustain life

      • Without digestive enzymes, one meal would take around 2–3 weeks to digest; with enzymes it takes 3-4 hours

How do enzymes work?

Diagram showing a yellow substrate that has a complementary shape with enzyme 1 on the bottom left but not with enzyme 2 on the bottom right, illustrating complementary active site specificity for enzyme–substrate binding.
Enzyme substrate specificity
  • Enzymes are specific to one particular substrate (molecule/s that get broken down or joined together in the reaction) as the enzyme is a complementary shape to the substrate

  • The product is made from the substrate(s) and is released

Diagram showing the lock-and-key model of enzyme action, from top left labelled 1, where several yellow substrates and purple enzymes are complementary to each other and moving around in solution, bottom left labelled 2 with a single yellow substrate binding at the active site of a purple enzyme to form an enzyme–substrate complex and bottom right the separate products formed from the substate after it had formed a complex with the enzyme.
Enzyme specificity: lock and key model of enzyme activity

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Lára Marie McIvor

Author: Lára Marie McIvor

Expertise: Content Creator

Lára graduated from Oxford University in Biological Sciences and has now been a science tutor working in the UK for several years. Lára has a particular interest in the area of infectious disease and epidemiology, and enjoys creating original educational materials that develop confidence and facilitate learning.

Jenna Quinn

Reviewer: Jenna Quinn

Expertise: Content Creator

Jenna studied at Cardiff University before training to become a science teacher at the University of Bath specialising in Biology (although she loves teaching all three sciences at GCSE level!). Teaching is her passion, and with 10 years experience teaching across a wide range of specifications – from GCSE and A Level Biology in the UK to IGCSE and IB Biology internationally – she knows what is required to pass those Biology exams.