Amino Acids (AQA GCSE Chemistry)

Revision Note

Stewart Hird

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Amino Acids

Higher tier only

  • Amino acids are small molecules containing the amino, NH2, and carboxylic acid, COOH, functional groups

  • The NH2 group is basic and behaves in a similar way to ammonia

  • The COOH group is acidic and is called a carboxyl group

  • There are twenty naturally occurring amino acids and they all have the same general structure

The general structure of an amino acid 

Amino acid general formula

The structure of naturally occurring amino acids have an amino group on the second carbon along from the carboxyl group. The R represents a varying side group.

Polypeptides

  • Polypeptides are condensation polymers which are formed from amino acid monomers joined together by peptide links

  • In polypeptides the amino group on one amino acid links to the acid group of an adjacent amino acid

Peptide link in proteins

Diagram showing a peptide link which holds proteins together

  • This pattern continues to form the polymer chain with one water molecule being lost per peptide link

  • Proteins are one or more long-chains of polypeptides

  • Most proteins contain at least 20 different amino acids

  • Polypeptides and proteins can contain different amino acids in their chains. The order of the amino acids determines the proteins structure and properties

Formation of a peptide bond

Formation of a protein from amino acids

Diagram showing condensation polymerisation to produce a protein

Examiner Tips and Tricks

When drawing biological polymers it is important that you show the peptide link clearly in your sketch.

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Stewart Hird

Author: Stewart Hird

Expertise: Chemistry Lead

Stewart has been an enthusiastic GCSE, IGCSE, A Level and IB teacher for more than 30 years in the UK as well as overseas, and has also been an examiner for IB and A Level. As a long-standing Head of Science, Stewart brings a wealth of experience to creating Topic Questions and revision materials for Save My Exams. Stewart specialises in Chemistry, but has also taught Physics and Environmental Systems and Societies.