How do Vaccines Work? (WJEC GCSE Biology)

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How Vaccines Protect Against Infection

Higher Tier Only

  • Vaccines can be given to protect people from the harmful symptoms of some bacterial or viral infections
  • Vaccines use bacterial or viral particles that are grown in a lab before being rendered harmless
  • They generally contain either:
    • Specific antigens derived from a pathogen
    • Parts of antigens
    • Non-active microorganisms, such as dead or weakened virus particles
  • These antigens or dead microorganisms are introduced into the body, usually in the form of an injection
  • Antigens and microorganisms in this form cannot cause illness but can provoke an immune response
  • Lymphocytes produce complementary antibodies for the antigens
  • The antibodies target the antigen and attach themselves to it which will then create memory cells
  • The memory cells remain in the blood and will quickly respond to the antigen if it is encountered again in an infection by a ‘live’ pathogen
  • As memory cells have been produced, this immunity is long-lasting

How vaccinations cause immunity

Vaccination containing antigens is introduced to trigger antibody production and memory cells

Vaccination

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Ruth

Author: Ruth

Expertise: Biology

Ruth graduated from Sheffield University with a degree in Biology and went on to teach Science in London whilst also completing an MA in innovation in Education. She gained 10 years of teaching experience across the 3 key science disciplines and physical education. Ruth decided to set up a tutoring business to support students in her local area. Ruth has worked with several exam boards and loves to use her experience to produce educational materials which make the mark schemes accessible to all students.