Biological Molecules (OCR GCSE Biology A (Gateway))
Revision Note
Sugars in Complex Carbohydrates
Carbohydrate molecules contain the elements carbon, hydrogen and oxygen
In the human body, carbohydrates are broken down by enzymes in the mouth and small intestine
Carbohydrates can be classed into different groups (monosaccharides, disaccharides and polysaccharides) depending on their complexity
Monosaccharides are simple sugars that consists of a single monomer unit e.g. glucose (C6H12O6) or fructose
Glucose molecules contain lots of energy which can be released in respiration by breaking the bonds between the carbon atoms
A disaccharide is made when two monosaccharides join together
Maltose is formed from two glucose molecules
Sucrose is formed from one glucose and one fructose molecule
A polysaccharide is formed when lots of monomer units join together in long chains to form a polymer
Starch, glycogen or cellulose are all formed when lots of glucose molecules join together
Polysaccharides are insoluble and therefore useful as storage molecules
Glycogen, cellulose and starch are all made from glucose molecules
Amino Acids in Proteins
Proteins are polymers formed from long chains of monomers called amino acids joined together
Amino acids contain carbon, nitrogen, hydrogen and oxygen atoms
Just 20 different standard amino acids make up all the proteins found in the human body (although many more amino acids occur in nature)
Amino acids can be arranged in any order, resulting in hundreds of thousands of different proteins
Examples of proteins include enzymes, haemoglobin, ligaments and keratin
In the human body, proteins that we ingest are broken down into the constituent amino acids
Enzymes in the stomach and small intestine break down the protein
These amino acids can then be used in the synthesis of new proteins
Amino acids join together to form proteins
Protein shape
Different proteins have different amino acid sequences resulting in the peptide chain folding into different shapes
The function of a protein is determined by its shape
Even a small difference in the amino acid sequence will result in a completely different protein being formed
In this way, every protein has a unique 3-D shape that enables it to carry out its function
Fatty Acids & Glycerol in Lipids
Lipids (fats and oils) are made up of triglycerides
Their basic unit is one glycerol molecule chemically bonded to three fatty acid chains
Lipids contain carbon, hydrogen and oxygen atoms
Unlike carbohydrates and proteins, they don't form polymers (they don't form a long chain of repeating sub-units)
Lipids are divided into fats (solids at room temperature) and oils (liquids at room temperature)
In the human body lipids are broken down by enzymes called lipases in the small intestine
The structure of a triglyceride
Examiner Tips and Tricks
You should be able to explain the importance of sugars, amino acids, fatty acids and glycerol in the synthesis and breakdown of carbohydrates, proteins and lipids. There will be many examples of each of these molecules throughout the course. You will not need to remember the molecular structure.
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