Human Endocrine System (AQA GCSE Biology)

Revision Note

Lára Marie McIvor

Written by: Lára Marie McIvor

Reviewed by: Lucy Kirkham

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Endocrine System Structure & Function

  • The human endocrine system is composed of glands which secrete chemicals called hormones directly into the bloodstream

  • The blood carries the hormone around the body, and when it reaches a target cell/organ it produces an effect

  • Compared to the nervous system the effects of hormones are slower but they act for longer

  • Important structures in the endocrine system are:

    • Pituitary gland: a ‘master gland’ making hormones such as FSH and LH

    • Pancreas: produces insulin which regulates the blood glucose level

    • Thyroid: produces thyroxine which controls metabolic rate and affects growth

    • Adrenal glands: produces adrenaline

    • Ovaries (females): produce oestrogen

    • Testes (males): produce testosterone

The major endocrine glands in the body, IGCSE & GCSE Biology revision notesThe major endocrine glands in the body, IGCSE & GCSE Biology revision notes

The major endocrine glands in the body secrete hormones which circulate around the body in the bloodstream

Examiner Tips and Tricks

Make sure you can recognise the structures listed in the diagram above in the exam.

Pituitary Gland

  • The pituitary gland in the brain is a ‘master gland’ which secretes several hormones into the blood in response to body conditions

  • These hormones in turn act on other glands to stimulate other hormones to be released to bring about effects

    • For example, in certain conditions, the pituitary gland makes and secretes thyroid-stimulating hormone (TSH) which stimulates the thyroid to release thyroxine

How hormones work, IGCSE & GCSE Biology revision notes

Hormones are synthesized and released into the bloodstream from a gland (such as the pituitary gland) and circulate in the bloodstream, having an effect on target cells

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Lára Marie McIvor

Author: Lára Marie McIvor

Expertise: Biology Lead

Lára graduated from Oxford University in Biological Sciences and has now been a science tutor working in the UK for several years. Lára has a particular interest in the area of infectious disease and epidemiology, and enjoys creating original educational materials that develop confidence and facilitate learning.

Lucy Kirkham

Author: Lucy Kirkham

Expertise: Head of STEM

Lucy has been a passionate Maths teacher for over 12 years, teaching maths across the UK and abroad helping to engage, interest and develop confidence in the subject at all levels.Working as a Head of Department and then Director of Maths, Lucy has advised schools and academy trusts in both Scotland and the East Midlands, where her role was to support and coach teachers to improve Maths teaching for all.