Metabolism (AQA GCSE Biology)
Revision Note
Written by: Lára Marie McIvor
Reviewed by: Lucy Kirkham
Metabolism: Basics
What is metabolism?
Metabolism can be defined as
the sum of all the reactions in a cell or the body
Metabolic reactions happen all of the time powered by energy transferred by respiration in cells
Enzyme-controlled processes use this energy in metabolism to synthesise new molecules
Metabolic reactions are often linked, where the products of one reaction are the reactants for another
Metabolic substrates
Metabolic reactions include the synthesis and breakdown of carbohydrates, lipids and proteins
Glucose (a sugar) is used in the synthesis of starch, glycogen or cellulose
Fatty acids and glycerol are used in the synthesis of lipids
Amino acids are used in the synthesis of proteins
These substances act as substrates in many key reactions
Metabolic reactions
The products of digestion are used to build substances, and some of these are then broken down – this is metabolism
Examiner Tips and Tricks
You should be able to explain the importance of sugars, amino acids, fatty acids and glycerol in the synthesis and breakdown of carbohydrates, proteins and lipids.
Examples of metabolic reactions
Metabolism includes:
Conversion of glucose to cellulose in plants to build and strengthen cell walls
Conversion of glucose into glycogen in animals and starch in plants for storage
The formation of lipid molecules from a molecule of glycerol and three molecules of fatty acids to form triglycerides which are used for energy storage and as insulation in animals
In plants: the use of glucose and nitrate ions to form amino acids which in turn are used to synthesise proteins required by cells (such as enzymes)
Glucose is broken down in the process of respiration to release energy in all cells
In animals, the breakdown of excess proteins to form urea for excretion
Examiner Tips and Tricks
All of the features of metabolism listed are covered in more detail in the relevant topics but you should be aware of how they all link together here.
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