The Heart (AQA GCSE Biology): Revision Note
Exam code: 8461
The heart
The heart is an organ that pumps blood around the body
It is part of the circulatory system, which contains:
blood vessels
a pump (the heart)
valves that maintain a one-way flow of blood around the body
Double circulatory system
The human heart is part of a double-circulatory system, meaning that:
it consists of two circuits; one to the body and one to the lungs
blood passes through the heart twice for every complete journey around the body
The heart has four chambers; two on the right and two on the left:
The right side of the heart pumps blood to the lungs for gas exchange; this is the pulmonary circuit
The left side of the heart pumps blood to the body; this is the systemic circuit
The benefits of a double circulatory system include:
Blood is sent to the lungs at a lower pressure, protecting delicate lung capillaries from damage while allowing sufficient time for gas exchange
Returning blood to the heart to be pumped a second time increases its pressure before it travels to the rest of the body; cells can therefore be supplied with oxygen more quickly
The heart structure prevents oxygenated blood from mixing with deoxygenated blood, ensuring that cells receive fully oxygenated blood
Heart structure
The heart has four chambers; two upper atria and two lower ventricles
Atria: receive blood from the body or the lungs and pass it to the ventricles
Ventricles: receive blood from the atria and pump it to the lungs / body
The right side of the heart contains deoxygenated blood
The left side of the heart contains oxygenated blood
Blood travels towards the heart in veins
Vena cava: blood travels from the body back towards the heart
Pulmonary vein: blood travels from the lungs to the heart
The blood is pumped away from the heart in arteries
Aorta: blood is pumped out of the heart towards the body
Pulmonary artery: blood is pumped out of the heart towards the lungs
The heart muscle itself is supplied with blood by the coronary arteries
Blood in the coronary arteries supplies oxygen and nutrients and removes waste carbon dioxide


Examiner Tips and Tricks
It can be easy to get confused about left and right when looking at diagrams of the heart. Remember that:
heart diagrams are drawn as if you are facing the person whose heart it is — so the right side of their heart appears on the left of the page, and vice versa
if the diagram is anatomically correct, the left ventricle will always have the thickest wall, because it pumps blood the furthest
Pathway of blood through the heart
Deoxygenated blood enters the heart via the vena cava, emptying into the right atrium
Blood flows through a set of valves into the right ventricle
When the right ventricle contracts, blood travels up through the pulmonary artery to the lungs, where gas exchange occurs
Oxygenated blood returns to the heart via the pulmonary vein, emptying into the left atrium
Blood flows through another set of valves into the left ventricle
When the left ventricle contracts, blood travels up through the aorta, and to the rest of the body
Examiner Tips and Tricks
In reality the events in the left and right sides of the heart happen simultaneously, so:
both atria fill at the same time
both ventricles fill at the same time
left and right ventricles contract simultaneously to push blood out of the heart
Adaptations of the heart
The structure of the heart ensures that blood is pumped efficiently:
Differences in muscle thickness
The walls of the ventricles are much thicker than those of the atria as they need to pump blood out of the heart at a higher pressure
The wall of the left ventricle is much thicker than that of the right ventricle as it has to pump blood at high pressure around the entire body
Maintenance of correct blood flow
Two sets of valves inside the heart which prevent the backflow of blood
Separation of left and right
A muscle wall between left and right chambers prevents the mixing of deoxygenated and oxygenated blood inside the heart
If blood were to mix then less oxygenated blood would be pumped around the body
Heart rate
The resting heart rate is controlled by a group of cells located in the right atrium
These cells form a structure called the pacemaker
The role of the pacemaker is to coordinate the contraction of the heart muscle, therefore it regulates the heart rate
The faster the heart contracts, the more quickly oxygenated blood can be delivered around the body
When a person is at rest, the oxygen demand of their cells is relatively low and so a lower heart rate is maintained
When a person is exercising, the oxygen demand of their muscle cells increases so a higher heart rate is necessary
The pacemaker sends out an electrical impulse which spreads to the surrounding muscle cells of the heart, causing them to contract
The pacemaker does this every time the heart needs to beat, so if a person has a resting heart rate of 60 beats per minute (bpm), then the pacemaker will be sending out electrical impulses on average once every second
Examiner Tips and Tricks
The pacemaker is located in the wall of the right atrium – you may be asked to locate it on a diagram in the exam.
Artificial pacemakers
Sometimes, the pacemaker of the heart stops functioning properly
This can cause an irregular heartbeat
Artificial pacemakers are electrical devices used to correct irregularities in the heart rate
The device is implanted just under the skin, with a wire that delivers an electrical current to the heart to help it contract regularly
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