Which of the following cells in the pancreas secrete insulin?
Alpha cells
Beta cells
Exocrine cells
All of the above
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Syllabus Edition
First teaching 2014
Last exams 2024
Which of the following cells in the pancreas secrete insulin?
Alpha cells
Beta cells
Exocrine cells
All of the above
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Which of the following statements (I - IV) correctly describe Type I diabetes?
I. It usually develops in those aged 40 and over, however more and more young people are developing the condition.
II. It is a condition in which the pancreas fails to produce sufficient insulin to control blood glucose levels.
III. It is normally treated with regular blood tests to check glucose levels, insulin injections, and a diabetes-appropriate diet.
IV. It is more common than Type II diabetes.
II and III
II, III and IV
I, III and IV
I and II
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The diagram below shows the male reproductive system.
Which row correctly identifies the structures?
I | II | III | IV | V | |
A. | Urethra | Sperm duct | Testis | Epididymis | Seminal vesicle |
B. | Seminal vesicle | Penis | Scrotum | Bladder | Testis |
C. | Sperm duct | Urethra | Seminal vesicle | Epididymis | Testis |
D. | Sperm duct | Urethra | Testis | Seminal vesicle | Epididymis |
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During which phase of the menstrual cycle does menstruation occur (approximately)?
Days 1 - 7
Days 7 - 14
Days 14 - 21
Days 21 - 28
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The peak in luteinising hormone (LH) during the menstrual cycle lead to which of the following events?
Stimulates the development of several immature egg cells in follicles in the ovary.
Stimulates the secretion of oestrogen by the follicle wall.
Stimulates the release of an egg into the oviduct.
Stimulates the endometrium to start thickening and the egg cell to mature.
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The following graph shows the hormones involved in the menstrual cycle.
Which line represents the hormone responsible for ovulation?
Line A.
Line B.
Line C.
Line D.
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Polycystic ovary syndrome (PCOS) is a condition which may affect certain women during their childbearing years. Some of the most common symptoms of this condition is a failure to ovulate and irregular menstrual cycles. Women with PCOS have an increased risk of developing endometrial cancer.
What would be the most appropriate explanation for this?
The endometrium will:
Build up due to the lack of ovulation.
Be shed too often.
Build up due to the lack of menstruation.
Be shed during ovulation.
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A person is admitted to hospital after suffering a stroke. It was found that the suprachiasmatic nucleus in the hypothalamus of the brain was damaged by the event. This resulted in the pineal gland secreting less melatonin into the bloodstream.
Which of the following changes would be observed in the patient?
Increased thirst and more frequent urination.
Disrupted sleep patterns and increased irritability.
Constantly feeling cold and weight gain.
Fatigue and forgetfulness.
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A condition known as congenital adrenal hyperplasia (CAH) may affect the development of the genitals in female fetuses. These children lack an enzyme necessary to produce the hormones cortisol and aldosterone. Without these hormones the fetus will produce more male sex hormones, such as testosterone, during their development.
What effect would this have on the development of a female fetus?
Sperm production would take place in the fetal gonads.
Delayed development of fetal genitalia.
Development of an abnormally large uterus.
Difficulty in identifying the fetus as female.
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The diagram shows the female reproductive system.
Which row correctly identifies the structures?
I | II | III | IV | V | |
A | Oviduct | Ovary | Uterus | Vagina | Cervix |
B | Ovary | Oviduct | Uterus | Vagina | Cervix |
C | Oviduct | Ovary | Uterus | Cervix | Vagina |
D | Oviduct | Ovary | Cervix | Uterus | Vagina |
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The following diagram shows the steps followed during in vitro fertilization.
Which row correctly identifies the steps?
I | II | III | |
A | Ovulation | Fertilization | Egg washing |
B | Ovulation | HCG injection | Fertilization |
C | HCG injection | Ovulation | Fertilization |
D | HCG injection | Egg washing | Fertilization |
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Which of the following are roles of thyroxin?
II only
I and II only
II and IV only
I, II, III and IV
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An obese patient participated in a drug trial to test the effectiveness of leptin injections to promote weight loss. After 12 weeks of receiving weekly leptin injections, the patient failed to lose any weight.
What could be the most plausible explanation for this outcome?
Target cells in the hypothalamus failed to respond to the leptin injections.
They have a mutation in the gene responsible for leptin synthesis.
Target cells in adipose tissue failed to respond to leptin injections.
Leptin is broken down too slowly by the body.
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A one year old child displays fatigue and excessive thirst over a period of time. A urine test reveals the presence of glucose.
Which of the following would be the most likely diagnosis?
Type I diabetes as the body is unable to respond to the presence of insulin.
Type I diabetes as the beta cells in the islets of Langerhans were destroyed.
Type II diabetes as the body does not have sufficient insulin receptors on target cells.
Type II diabetes as the alpha cells in the islets of Langerhans was destroyed.
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In which of the following scenarios would there be an increase in the breakdown of glycogen in the liver?
When the beta cells of the islets of Langerhans secrete insulin.
When the beta cells of the islets of Langerhans secrete glucagon.
After eating a meal high in carbohydrates.
When the alpha cells of the islets of Langerhans secrete glucagon.
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Which of the following statements about melatonin are correct?
I. Melatonin secretion increases in the evening in response to darkness and decreases at dawn in response to light.
II. Increasing melatonin levels stimulate the body, preparing it for waking up and staying awake during the day.
III. Melatonin is secreted by the hypothalamus.
IV. The night-time drop in core body temperature triggers an increase in melatonin secretion.
V. Melatonin levels vary during a 12-hour cycle known as a circadian rhythm.
II, IV and V
I, III and IV
I only
II and V
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Which of the statements below describe the hormone leptin?
I. This hormone is secreted by fat storage cells known as adipose cells.
II. This hormone's main role is to regulate the basal metabolic rate.
III. This hormone circulates in the blood and targets groups of cells in the hypothalamus.
IV. This hormone targets almost all cells in the body.
V. A deficiency in this hormone can lead to weight gain despite the loss of appetite.
I and V
I and III
II, IV and V
I, III and V
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Four hormones all interact to control the menstrual cycle via both negative and positive feedback.
Which of the below is an example of a negative feedback mechanism that occurs during the menstrual cycle?
Progesterone inhibiting oestrogen
Oestrogen inhibiting luteinizing hormone
Follicle stimulating hormone inhibiting oestrogen
Oestrogen inhibiting follicle stimulating hormone
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Identify the set of images that correctly shows follicle development during the course of the menstrual cycle.
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Which of the following statements is the most biologically correct?
The SRY gene codes for TDF, which inhibits the expression of further genes responsible for the development of ovaries, causing the foetal gonads to develop into testes.
The SRY gene codes for TDF, which stimulates the expression of further genes responsible for the development of testes, causing the foetal gonads to develop into testes.
The TDF gene codes for SRY, which stimulates the expression of further genes responsible for the development of testes, causing the foetal gonads to develop into testes.
The SRY gene codes for TDF, which inhibits the expression of further genes responsible for the development of testes, causing the foetal gonads to develop into ovaries.
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