Implantation of the Blastocyst
- Following human fertilisation, the newly fertilised ovum divides by mitosis to form two diploid nuclei (i.e. each nucleus contains two sets of chromosomes) and the cytoplasm divides equally to form a two-cell embryo
- Mitosis continues to form a four-cell embryo and this process continues until eventually, the embryo takes the shape of a hollow ball called a blastocyst (with an internal group of cells called blastomeres)
- Blastomeres will eventually develop into the foetus
- The embryo is now referred to as a blastocyst and up until this point is found in the oviduct
- After about seven days it consists of around 125 cells and will have reached the uterus
- During the embryo stage and up until this point the blastocyst is surrounded by a protective extracellular coat called the zona pellucida; at around seven days of age this coat breaks down and is lost
- The blastocyst has used up the nutrient supplies of the egg cell and now needs an external supply of nutrients, which it obtains by implanting into the endometrium (uterus lining)
- The outer layer of the blastocyst develops finger-like projections that allow it to penetrate the endometrium
- At this stage, there is already an exchange of nutrients and oxygen with the mother’s blood
- The embryo continues to grow and develop rapidly after this point
The blastocyst implants into the endometrium of the uterus