Homeostasis: Maintaining the Internal Environment (DP IB Biology): Revision Note
Maintaining the Internal Environment
- The process of maintaining a constant internal environment is known as homeostasis 
- Homeostasis ensures that conditions inside the body are kept within preset limits 
- Homeostasis is critically important for organisms as it ensures the maintenance of optimal conditions for enzyme action and cell function 
- Sensory cells can detect information about the conditions inside and outside the body; if conditions have changed then the body can respond to keep conditions constant 
- Examples of physiological factors that are controlled by homeostasis in mammals include - Core body temperature 
- Blood pH 
- Concentration of glucose in the blood 
- Osmotic concentration of the blood 
 
Negative Feedback Loops
- The majority of homeostatic control mechanisms in organisms use negative feedback loops to achieve homeostasis 
- Negative feedback mechanisms work to return values to a set point; they reverse the effects of any change within a system - Negative feedback loops are essential for maintaining conditions within set limits; this is not the case in positive feedback mechanisms which instead amplify any change 
 
- Negative feedback control loops involve: - A receptor – receptor cells detect change in a physiological factor 
- A coordination system – the brain and nervous system transfer information between different parts of the body 
- An effector – the muscles and glands bring about a response 
 
- Outcome of a negative feedback loop: - The factor / stimulus is continuously monitored 
- If there is an increase in the factor, the body responds to make the factor decrease 
- If there is a decrease in the factor, the body responds to make the factor increase 
 

Negative feedback loops maintain conditions to a set point
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