Syllabus Edition

First teaching 2023

First exams 2025

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Practice Paper 1A (SL IB Biology)

Practice Paper Questions

1
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The specific heat capacity of water is the highest of all liquids. Which of the following would be a correct definition of specific heat capacity? 

  • The heat required to change one mole of liquid into one mole of gas. 

  • The heat required to raise the temperature of 1kg of liquid by 1°C. 

  • The heat required to change one mole of solid into one mole of liquid.

  • The ability of a solid to transfer heat to a liquid. 

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2
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Which of the following drawings best represents the structure of a section of DNA?

2-6-biology-mcq-q6

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    3
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    A prokaryotic cell has a diameter of 1 µm. The cell is magnified ×50 000 by an electron microscope.

    In the electron micrograph that is produced by the electron microscope, what is the diameter of the prokaryotic cell?

    • 5 x 100 mm

    • 5 x 10-1 mm

    • 5 x 102 mm

    • 5 x 101 mm

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    4
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    Which set of observations would indicate that a student is observing a eukaryotic cell?

      Cytoplasm contains endoplasmic reticulum Protein molecules are associated with the DNA Diameter <1 µm
    A X X
    B X X
    C X
    D X X

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      5
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      Which is the correct definition for a species according to the biological species concept?

      • A group of organisms which look similar.

      • A group of organisms with similar characteristics.

      • A group of organisms which can interbreed to produce fertile offspring.

      • A group of living things.

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      6
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      Which of the following statements about selective breeding is correct?

      • Certain alleles are more likely to be passed on to offspring because they are advantageous and aid survival in an organism's environment

      • All of the offspring of the first generation are bred together to produce the second generation

      • Selective breeding is a recently developed technique

      • Crop varieties currently used by humans have been selectively bred from wild varieties

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      7
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      What is the most important requirement for speciation to occur?

      • A geographical barrier is needed to separate different species from one another so that natural selection can occur

      • Mutations occurring within a population which brings about slight changes to the phenotype of individuals

      • Reproductive isolation must occur within a population which can be brought about by a range of different barriers

      • Organisms must be able to find a suitable mate within their habitat in order to pass on their genetic information

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      8
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      Melanin is a dark pigment produced in the cells; higher melanin production results in an organism's darker colour.

      It has been noted that melanistic peppered moths have become more common than non-melanistic individuals in industrialised parts of the UK where air pollution has increased.

      Air pollution kills organisms, called lichens, that grow on the bark of trees. Areas with clean air have more lichen resulting in trees of a lighter colour compared to polluted areas where lichen are killed, causing tree trunks and branches to appear darker.

      Which of the following is not a reason for the evolution of melanism in peppered moths?

      • Predators such as birds act as a selection pressure, leading to differences in survival rates of moths with and without melanism.

      • Pollution from industry causes the death of lichens, leading to darkening of tree bark.

      • There is variation in the gene coding for melanin production in the moth population.

      • Some moths acquire darkened wings as a result of soot particles in the air, providing them with camouflage.

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      9
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      Which of the statements about conservation is correct?

      • The EDGE programme is concerned with conserving all evolutionarily distinct species.

      • In-situ conservation is appropriate for all endangered species.

      • Ex-situ conservation provides opportunities for important research.

      • Only body tissue can be stored in tissue banks.

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      10
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      The diagram below shows several different biological molecules (Q, R, S and T).

      kuoJPYLt_h-1

      Which row of the table below correctly identifies some of the products of hydrolysis of the molecules above?

        Q R S T
      A. α-glucose ß-glucose α-glucose glycerol
      B. α-glucose ß-glucose ß-glucose fatty acids
      C. ß-glucose α-glucose ß-glucose glycerol
      D. ß-glucose α-glucose α-glucose fatty acids

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        11
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        Which is the correct reason that cellulose passes through the gut undigested?

        • There are no enzymes present in the human digestive system capable of cellulose digestion.

        • Cellulose is not a required nutrient of the human body.

        • Cellulose provides bulk for effective peristalsis which forces the food through the alimentary canal.

        • It takes too long for the glucose monomers in cellulose to be hydrolysed, so cellulose is egested before it can be digested.

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        12
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        Amino acids consist of oxygen, hydrogen, carbon and nitrogen atoms. The diameter of each atom when bonded to another atom is shown in the table below.

        atom single bond / nm double bond / nm
        O 0.13 -
        H 0.06 0.110
        C 0.154 0.120
        N 0.14 0.134

        Using the figures in the table, the approximate length of one amino acid is 0.7 nm, as shown below.q1-2-3-proteins-medium-ib-hl-biology

        What would be the approximate length of a dipeptide of this amino acid after a condensation reaction has occurred?

        • 1.0 nm 

        • 1.2 nm

        • 1.4 nm

        • 1.6 nm 

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        13
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        What is the difference between simple diffusion and facilitated diffusion?

          Simple diffusion Facilitated diffusion
        A. Diffusion rate inversely proportional to concentration gradient Diffusion rate proportional to concentration gradient
        B. Never involves a membrane Always involves a membrane
        C. Occurs across any part of a membrane Occurs via channels in the membrane
        D. A passive process that does not require energy from ATP An active process that requires energy from ATP

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          14
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          The cells of bacteria are on average 1-5 µm long, whereas human cells are on average 100 µm in diameter. 

          What is the main limiting factor preventing the bacterial cells from growing to the same size as human cells? 

          • The rate of cell division would be too slow to allow colonisation of new areas

          • The structure of bacterial cell walls limits the size of the cell

          • A larger size would limit cell motility

          • The rate of diffusion at the cell surface does not increase quickly enough

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          15
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          An alveolus has several features to allow efficient gas exchange.

          7xBrVPfx_1

           

          Which row of the table below matches each feature of gas exchange to the correct label on the alveolus?

            I II III
          A High concentration of oxygen to maintain a steep concentration gradient One cell thick for short diffusion distance Allows gases to dissolve to aid diffusion
          B High concentration of carbon dioxide to maintain steep concentration gradient Allows gases to dissolve to aid diffusion One cell thick for short diffusion distance
          C One cell thick for short diffusion distance High concentration of oxygen to reduce the concentration gradient Allows gases to dissolve to aid diffusion
          D Allows gases to dissolve to aid diffusion Allows gases to dissolve to aid diffusion High concentration of oxygen to maintain a steep concentration gradient

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            16
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            The diagram shows a potometer set up to measure the rate of transpiration in a piece of cut plant. 

            potometer

            For a potometer with a cylindrical capillary of the internal diameter of d mm, the bubble was measured to travel h mm in an experimental time of s seconds. 

            Which is the correct formula to calculate the rate of transpiration (as a volume of water uptake per unit time) in this experiment?

            • fraction numerator pi italic space d to the power of italic 2 h over denominator s end fraction

            • pi italic space d to the power of italic 2 h space s

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            17
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            A group of scientists studied the distribution of an invertebrate species on a series of sandy beaches. Their results are shown in the graph.

            shoreline-transect-distribution-graph-1

            Which of the statements about the data is correct?

            • The data could have been collected using random quadrat sampling.

            • Conditions are outside the range of tolerance for the invertebrates at >15 m from the waterline on beach 3.

            • The number of invertebrates decreases as distance from the waterline increases.

            • Conditions are at their optimum for the invertebrate species at around 9 m from the waterline.

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            18
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            Which of the following statements about ecological niches is correct?

            • Competition reduces the size of an ecological niche.

            • An ecological niche can be shared between two similar species.

            • Competition for a niche always results in local extinction for one species.

            • A realised niche is larger than a fundamental niche.

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            19
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            When investigating the rate of reaction of the enzyme lipase on the hydrolysis of triglycerides, the pH must be maintained to prevent the lipase denaturing.

            Why might fluctuations in pH occur?

            • The products of hydrolysis will decrease the pH.

            • Lipase has a very low optimum pH.

            • The products of hydrolysis will increase the pH.

            • The water molecules produced as a byproduct of hydrolysis decreases pH.

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            20
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            The graph below shows the energy changes during a reaction.q3_8-1_metabolism_ib_biology_hl_mcq

            What effect would adding an enzyme have on the energy changes of the reaction?

            • Reduction in energy at A

            • Reduction in energy at B

            • Reduction in energy at C

            • Reduction in energy at D

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            21
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            The following graphs show the absorption spectrum for chlorophyll a and the action spectrum showing the relative rate of photosynthesis at different wavelengths of light.

            biology-2-8-q6-ib-hl-

            Why do the graphs look different?

            • Other pigments are involved in photosynthesis which can absorb light of different wavelengths.

            • Only visible light is absorbed by photosynthetic pigments.

            • Photosynthesis can only occur in blue and red wavelengths of light.

            • Chlorophyll a inhibits the absorption of green and yellow light.

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            22
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            The image below shows a petri dish viewed from above. A lawn of bacteria is growing across the whole surface of the agar. 

            Different antibiotics, X and Y were applied to the agar before inoculating it with bacteria. Both antibiotics were applied to the discs of filter paper at the same concentration. 

            The plates were then incubated for 24 hours at 25°C. Zones of inhibition (areas of the dish with no bacterial growth) are shown on the diagram. cNjoDURL_h-2

            After growth, the following results were obtained. 

            Antibiotic Diameter of zone of inhibition / cm
            X 2.0
            Y 6.0

            How many times more effective was antibiotic Y versus antibiotic X in this study? 

            • 12×

            • 18×

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            23
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            The pneumococcal conjugate vaccine (PCV13) provides protection against infection caused by the bacterium Streptococcus pneumoniae. The graph shows the number of cases of invasive pneumococcal disease (IPD) caused by antibiotic resistant S. pneumoniae before and after the introduction of PCV13.

            h-4-2

            Which statement correctly explains the number of cases of IPD caused by antibiotic resistant S. pneumoniae after the introduction of PCV13?

            • The vaccine is killing the bacteria that cause the infections.

            • The vaccine has reduced the use of antibiotics, meaning that resistance alleles are no longer advantageous.

            • The vaccine has reduced the use of antibiotics and the bacteria respond by becoming less resistant.

            • The vaccine has reduced the use of antibiotics, preventing resistance alleles from being passed on when bacteria divide. 

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            24
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            A chi-squared test was carried out to test for association between species A and species B.  The results of the chi-squared test are given below. 

            Results of chi-squared test:

            Chi-squared value 5.89
            Degrees of freedom 1

            Critical values table:

            Degrees of freedom Probability level
            0.1 0.05 0.01 0.001
            1 2.71 3.84 6.64 10.83
            2 4.60 5.99 9.21 13.82

            What can be concluded from the chi-squared test for association carried out to test for association between species A and species B?

            • There is no significant association between species A and species B

            • Species A competes with species B for resources

            • There is a statistically significant association between species A and species B at the 5% probability level

            • There is a statistically significant association between species A and species B at the 1% probability level

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            25
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            The graph shows changes in percentage cover of four plant species on a sand dune ecosystem over 500 years.

            w4Tj9cFV_h-3

            Which of the following explanations cannot be supported using the information in this graph.

            • All four species never formed part of the same community

            • Beech grass became extinct after 100 years

            • Interspecific competition between conifer trees and shrub bunchgrass occurs leading to a decrease in shrub bunchgrass

            • Intraspecific competition results in a decrease in conifer trees after around 400 years

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            26
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            Which row of the table correctly identifies an observation of food chains and the theory used to explain that observation?

              Observation Theory
            I Food chains are short Energy losses occur at each trophic level
            II Food chains have a pyramid structure Organisms with a larger biomass provide more energy to the next trophic level
            III Food chains all start with a producer Producers transfer energy most efficiently
            IV Energy losses occur at each trophic level Energy is transferred to the surroundings during respiration 
            • I only

            • I and IV

            • II and IV

            • I and III

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            27
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            When DNA polymerase adds a new nucleotide to a growing DNA strand, which part of the last nucleotide does it form a bond with?

            • Nitrogenous base

            • 5’ phosphate group of a pentose sugar

            • 1’ Carbon of a pentose sugar

            • 3’ -OH group of a pentose sugar

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            28
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            The pedigree chart below shows the inheritance of Tay-Sachs disease which is an autosomal recessive trait, characterised by neurological problems caused by the death of nerve cells. 

            In the pedigree chart, a filled in circle or square means the individual is affected and shows the genetic condition.

            What is the probability that individuals 3 and 4 will have another child with Tay-Sachs disease?

            UpV6A5dP_h-2

            • 25%

            • 50%

            • 75%

            • 100%

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            29
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            A one year old child displays fatigue and excessive thirst over a period of time. A urine test reveals the presence of glucose.

            Which of the following would be the most likely diagnosis?

            • Type I diabetes as the body is unable to respond to the presence of insulin.

            • Type I diabetes as the beta cells in the islets of Langerhans were destroyed.

            • Type II diabetes as the body does not have sufficient insulin receptors on target cells.

            • Type II diabetes as the alpha cells in the islets of Langerhans was destroyed.

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            30
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            Which of the following is not true about mesocosms?

            • Mesocosms allow the control of environmental conditions

            • Mesocosms allow collection of reliable data

            • Continuous data can be collected from a mesocosm

            • It is easy to mimic natural environmental conditions in a mesocosm

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