Perception of Pain
- Pain receptors (nociceptors) are sensory receptors
- These receptors have free nerve endings which are unencapsulated nerve endings
- The exposed dendrites on these nerves have transient receptor potential (TRP) channels which open in response to stimuli which indicate a risk of damaged tissue
- Stimuli might include:
- High temperature
- Acid
- Chemicals e.g. capsaicin in chilli peppers
- Entry of positively charged ions causes the threshold potential to be reached
- An action potential is generated, it moves along the axon of the sensory neurone to the central nervous system
- Nerve impulses then pass through the neurones to the cerebral cortex in the brain, where pain is perceived and a protective response results
- The sensitivity of an organism to these stimuli provides a survival and reproductive advantage
Pain Receptors Diagram
Pain receptors in the skin can respond to a number of different stimuli as the nerve endings are exposed