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First exams 2025

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Cell Adhesion (HL) (HL IB Biology)

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Cara Head

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Cara Head

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Cell Adhesion

  • In order for an organism to be multicellular, its cells need to adhere, or stick, to one another to form tissues
  • The plasma membrane is responsible for cell adhesion and this can be permanent or temporary
  • Cell adhesion molecules (CAMs) are required to carry out cell adhesion
    • CAMs are a type of cell surface protein
    • They work by binding cells with other cells or with the extracellular matrix
      • The extracellular matrix contains supporting structures, such as collagen proteins, and provides support for the cells
    • Different CAMs are present in different types of cell-cell junction
  • Examples of different cell-cell junctions include:
    • Tight junctions
    • Adherens junctions
    • Desmosomes
    • Gap junctions

Cell adhesion diagram

b2-1-17-adhesion-of-cells-to-form-tissues

Cell adhesion involves the binding of CAMs to other cells or to the extra-cellular matrix

Different types of cell-cell junction contain different CAMs

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Cara Head

Author: Cara Head

Expertise: Biology

Cara graduated from the University of Exeter in 2005 with a degree in Biological Sciences. She has fifteen years of experience teaching the Sciences at KS3 to KS5, and Psychology at A-Level. Cara has taught in a range of secondary schools across the South West of England before joining the team at SME. Cara is passionate about Biology and creating resources that bring the subject alive and deepen students' understanding