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First teaching 2023

First exams 2025

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Circulatory Systems (CIE AS Biology)

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Closed Double Circulatory System

The need for a circulatory system

  • The cells of all living organisms need a constant supply of reactants for metabolism, e.g. oxygen and glucose
  • Single celled organisms can gain oxygen and glucose directly from their surroundings, and the molecules can diffuse to all parts of the cell quickly due to short diffusion distances
  • Larger organisms, however, are made up of many layers of cells, meaning that the time taken for substances such as glucose and oxygen to diffuse to every cell in the body would be far too long
    • The diffusion distances involved are too great
  • To solve this problem their exchange surfaces are connected to a mass transport system, for example
    • The digestive system is connected to the circulatory system
    • The lungs are connected to the circulatory system
  • Mass transport is the bulk movement of gases or liquids in one direction, usually via a system of vessels and tubes
  • The circulatory system in mammals is a well-studied example of a mass transport system; the one-way flow of blood within the blood vessels carries essential nutrients and gases to all the cells of the body

Open & closed systems

  • Circulatory systems are either described as being open or closed
  • In a closed circulatory system, blood is pumped around the body and is always contained within a network of blood vessels
    • All vertebrates and many invertebrates have closed circulatory systems
  • In an open circulatory system, blood is not contained within blood vessels but is pumped directly into body cavities
    • Organisms such as arthropods and molluscs have open circulatory systems
  • Humans have a closed double circulatory system: in one complete circuit of the body blood passes through the heart (the pump) twice
  • The right side of the heart pumps deoxygenated blood to the lungs for gas exchange; this is the pulmonary circulatory system
  • Blood then returns to the left side of the heart, so that oxygenated blood can be pumped efficiently (at high pressure) around the body; this is the systemic circulatory system

The double circulatory system in mammals

The double circulatory system in mammals with systemic and pulmonary circulation

The double circulatory system in mammals showing pulmonary and systemic circulation

Main circulatory system structures table

Structure Function
Heart A hollow, muscular organ located in the chest cavity which pumps blood. Cardiac muscle tissue is specialised for repeated involuntary contraction without rest.
Arteries Blood vessels which carry blood away from the heart. The walls of the arteries contain lots of muscle and elastic tissue and a narrow lumen,  to maintain high blood pressure. Arteries range from 0.4 - 2.5cm in diameter.
Arterioles Small arteries which branch from larger arteries and connect to capillaries. These are around 30μm in diameter.
Capillaries Tiny blood vessels (5-10μm in diameter) which connect arterioles and venules. Their size means they pass directly past cells and tissues and perform gas exchange and exchange of substances such as glucose.
Venules Small veins which join capillaries to larger veins. They have a diameter of 7μm - 1mm.
Veins Blood vessels which carry blood back towards the heart. The walls of veins are thin in comparison to arteries, having less muscle and elastic tissue but a wider lumen. Valves help maintain blood flow back towards the heart.

Examiner Tip

Organisms that respire aerobically require oxygen to release energy from the breakdown of glucose and other organic substances, but oxygen is not the only substance that needs to be transported around an organism by a circulatory system.

Make sure you study any circulatory diagrams in the exam carefully to distinguish between single and double circulatory systems and to discern between pulmonary and systemic circulation.

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Emma

Author: Emma

Expertise: Biology

Prior to working at SME, Emma was a Biology teacher for 5 years. During those years she taught three different GCSE exam boards and two A-Level exam boards, gaining a wide range of teaching expertise in the subject. Emma particularly enjoys learning about ecology and conservation. Emma is passionate about making her students achieve the highest possible grades in their exams by creating amazing revision resources!