Differences Between Prokaryotic & Eukaryotic Cells (College Board AP® Biology)

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Written by: Phil

Reviewed by: Lára Marie McIvor

Prokaryotes & Eukaryotes

  • Animal and plant cells are types of eukaryotic cells, whereas bacteria are a type of prokaryote

  • Prokaryotes have a cellular structure distinct from eukaryotes:

    • Their genetic material is not packaged within a membrane-bound nucleus and is usually circular (eukaryotic genetic material is packaged as linear chromosomes)

    • Prokaryotes lack membrane-bound organelles

    • Eukaryote cells are compartmentalized to create partitions within the cell for specialized reactions to take place

    • Prokaryote cells are many (100s/1000s) of times smaller than eukaryotic cells

    • Their ribosomes are structurally smaller (70 S) in comparison to those found in eukaryotic cells (80 S)

A Prokaryotic Cell's Structural Features Diagram

prokaryotic-cell-structural-features

Prokaryotic cells are often described as being ‘simpler’ than eukaryotic cells, and they are believed to have emerged as the first living organisms on Earth.

Prokaryotic & Eukaryotic Cells Comparison Table

FEATURE

PROKARYOTES

EUKARYOTES

Size

0.5 - 5 µm diameter

Up to 100 µm diameter

Genome

DNA circular with no proteins, in the cytoplasm

DNA is associated with histones (proteins), formed into chromosomes

Cell division

Occurs by binary fission, no spindle involved

Occurs by mitosis or meiosis and involves a spindle to separate chromosomes

Ribosomes

70S ribosomes

80S ribosomes

Organelles

Very few
No membrane-bound organelles

Numerous types of organelle
Membrane-bound
Single membranes: lysosomes, Golgi, vacuoles
Double membranes: nucleus, mitochondria, chloroplast
No membrane: ribosome, centriole, microtubules

Cell wall

Made of peptidoglycan (polysaccharide and amino acids) and murein

Present in plants (made of cellulose or lignin) and fungi (made of chitin, similar to cellulose but contains nitrogen)

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Phil

Author: Phil

Expertise: Biology Content Creator

Phil has a BSc in Biochemistry from the University of Birmingham, followed by an MBA from Manchester Business School. He has 15 years of teaching and tutoring experience, teaching Biology in schools before becoming director of a growing tuition agency. He has also examined Biology for one of the leading UK exam boards. Phil has a particular passion for empowering students to overcome their fear of numbers in a scientific context.

Lára Marie McIvor

Author: Lára Marie McIvor

Expertise: Biology Lead

Lára graduated from Oxford University in Biological Sciences and has now been a science tutor working in the UK for several years. Lára has a particular interest in the area of infectious disease and epidemiology, and enjoys creating original educational materials that develop confidence and facilitate learning.