Exocytosis & Endocytosis (College Board AP® Biology): Study Guide

Naomi Holyoak

Written by: Naomi Holyoak

Reviewed by: Ruth Brindle

Updated on

Exocytosis & endocytosis

  • The processes of exocytosis and endocytosis allow the transport of large molecules across the plasma membrane

    • They can also allow for the transport of whole cells, or parts of cells

  • Exocytosis and endocytosis require energy, so they are forms of active transport

Exocytosis

  • Exocytosis is the process by which large macromolecules are transported out of cells:

    • The substance to be released is packaged into internal vesicles

    • These vesicles then travel to the cell surface membrane where they fuse with the membrane and secrete their contents outside the cell

  • Examples of exocytosis include:

    • the release of neurotransmitters during nerve impulse transmission

    • the secretion of insulin during blood glucose regulation

    • enzyme secretion in the digestive system

Endocytosis

  • Endocytosis is the process by which cells take in macromolecules and particulate matter:

    • During endocytosis the plasma membrane engulfs material, forming a new vesicle from the membrane

    • The vesicle then carries the imported substance into the cell

  • Examples of endocytosis include:

    • phagocytosis, during which cells of the immune system engulf and destroy pathogens

    • the ingestion of cholesterol in order to build new membranes

    • taking in water

Diagram illustrating exocytosis and endocytosis processes, showing cellular transport across the plasma membrane between cytoplasm and extracellular fluid.
Exocytosis and endocytosis use energy to transport large macromolecules across cell membranes; both processes involve vesicles which fuse with, or form from, the cell surface membrane

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Naomi Holyoak

Author: Naomi Holyoak

Expertise: Biology

Naomi graduated from the University of Oxford with a degree in Biological Sciences. She has 8 years of classroom experience teaching Key Stage 3 up to A-Level biology, and is currently a tutor and A-Level examiner. Naomi especially enjoys creating resources that enable students to build a solid understanding of subject content, while also connecting their knowledge with biology’s exciting, real-world applications.

Ruth Brindle

Author: Ruth Brindle

Expertise: Biology

Ruth graduated from Sheffield University with a degree in Biology and went on to teach Science in London whilst also completing an MA in innovation in Education. With 10 years of teaching experience across the 3 key science disciplines, Ruth decided to set up a tutoring business to support students in her local area. Ruth has worked with several exam boards and loves to use her experience to produce educational materials which make the mark schemes accessible to all students.