The Role of Chromosomes & Hormones (AQA A Level Psychology)

Revision Note

Laura Swash

Written by: Laura Swash

Reviewed by: Lucy Vinson

The role of chromosomes in sex & gender

  • Chromosomes are made of nucleic acids (mainly DNA in humans) and protein and are found in the nucleus of cells

  • Humans have 23 pairs of chromosomes in each cell (the 23rd pair determines the baby’s sex) with the chromosome pattern for a male being XY (one of the pair looks like and X and one like a Y) and for a female it is XX

  • Chromosomes determine a baby’s sex at fertilisation: all eggs carry an X chromosome, and if the egg is fertlised by a Y-chromosome carrying sperm, the the child will be a male and if the sperm carries an X chromosome, then the baby will be female

  • During prenatal development, individuals have gonads which are identical and have the ability to turn into either testes or ovaries, so if a Y chromosome is present it produces a protein which causes the gonads to become testes

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The 23rd chromosome pair of a male 

The role of hormones in sex & gender

  • Hormones are chemical messengers that are released into the bloodstream from glands

  • The main sex hormones are

    • Testosterone - which stimulates the development of male characteristics and is produced in the testes

    • Oestrogen - which stimulates the development of female characteristics and is produced in the ovaries

    • Oxytocin - is produced in the hypothalamus and controls key aspects of the reproductive system (though testosterone inhibits its action in males) especially labour and breast-feeding in mothers, as well as nurturing behaviour in both sexes

  • When it comes to determining the sex of a foetus, the chromosomes control the hormone action that decides if the gonads become testes or ovaries

  • When the Y chromosome of the foetus in the womb is detected by the baby’s brain, approximately two months after conception, this slows down the oestrogen production that until then has been present in both the XX and the XY foetus, and increases testosterone production and the baby continues to grow as a boy

  • If no Y chromosome is detected, then the oestrogen production continues and the baby develops ovaries and the characteristics of a girl

  • The hormonal differences in XX and XY foetuses result in physical differences in bone and muscle growth and body shape 

  • Testosterone affects the size of the suprachiasmatic nucleus (SDN): a brain area associated with our psychological gender identity, making it larger in males than in females 

  • This may contribute to some of our psychological gender differences, though many psychologists debate whether functionally there is any difference between male and female brains

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Though it is determined much earlier, a baby’s sex can usually be identified in the 18-20 week scan.

Examiner Tips and Tricks

If you are asked a question on the role of chromosomes and hormones in gender development, remember that although chromosomes initially determine a person's sex, most gender development is actually governed by hormones, so you will need to know them in detail: 

  • Testosterone is easy to remember because of its link with testes

  • Oestrogen is produced in the ovaries

  • Oxytocin is produced in the brain, but is more active in women

If you think of the first letter of each (and the ‘o’ in ‘women’), that will help you recall to which sex they apply most. (Remember that both males and females have some of each hormone).

Research which investigates chromosomes and hormones

  • Van Goozen et al. (1995) found transgender women (male-to-female) who were given oestrogen treatment showed decreases in aggression and visuospatial skills, while transgender men (female-to-male) treated with testosterone showed the opposite effects 

  • Deady et al. (2006) conducted a correlational study in which they measured 27 young women’s testosterone levels, gave them the Bem Sex-role Inventory with extra questions about their mothering intentions and ambition to have children and found that high testosterone levels correlated with a low desire for children

To identify all behaviour differences between males and females as being a result of their different chromosomes and hormones is biological determinism. This refers to the idea that all human behaviour is innate and it ignores the role of the environment, culture and socialisation in gendered behaviour. The idea that all human behaviour is innate is a form of hard determinism that views sex and gender as directly linked and something over which the individual has no control. Male and female sex determines gender which just becomes visible masculinity and femininity with associated personality traits, bodily strength and feminine and masculine choices of ways of life, including careers, childcare and preferred activities.

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Laura Swash

Author: Laura Swash

Expertise: Psychology Content Creator

Laura has been teaching for 31 years and is a teacher of GCSE, A level and IB Diploma psychology, in the UK and overseas and now online. She is a senior examiner, freelance psychology teacher and teacher trainer. Laura also writes a blog, textbooks and online content to support all psychology courses. She lives on a small Portuguese island in the Atlantic where, when she is not online or writing, she loves to scuba dive, cycle and garden.

Lucy Vinson

Author: Lucy Vinson

Expertise: Psychology Subject Lead

Lucy has been a part of Save My Exams since 2024 and is responsible for all things Psychology & Social Science in her role as Subject Lead. Prior to this, Lucy taught for 5 years, including Computing (KS3), Geography (KS3 & GCSE) and Psychology A Level as a Subject Lead for 4 years. She loves teaching research methods and psychopathology. Outside of the classroom, she has provided pastoral support for hundreds of boarding students over a four year period as a boarding house tutor.