The Molybdenum-Technetium Generator (AQA A Level Physics)

Revision Note

Dan Mitchell-Garnett

Last updated

The Molybdenum-Technetium Generator

  • A molybdenum–technetium generator is a device that produces technetium from molybdenum

  • Technetium-99m (Tc-99) has a half-life of 6.0 hours

    • This allows it to be used as a tracer with low irradiation of the patient, thanks to the short half-life

    • The short half-life, however, means it must be produced in the hospital when needed, as it cannot maintain the required levels of radioactivity for long periods of time

  • Molybdenum-99 (Mo-99) has a half-life of 66 hours (2.8 days)

    • It is produced in nuclear reactors, and due to its slightly longer half-life, it can be transported to hospitals every week

  • Once Mo-99 arrives at a hospital, it can be placed in a molybdenum-technetium generator to produce Tc-99m

  • In the generator, Mo-99 decays over the course of a few days, producing Tc-99m for up to a week

    • Tc-99m is extracted from the generator every few days by passing a saline solution over the radioactive materials

    • Tc-99m enters the solution, which can then be extracted and injected into patients ready for scanning

Worked Example

A medic suggests that the molybdenum-technetium generator should be kept at the nuclear power station and Tc-99m should just be shipped into the hospital. 

It is a 12 hour journey for a truck from the nearest nuclear power station.

Calculate the percentage of Tc-99m lost in the process of supplying the hospital with 1 kg of Tc-99m.

The half-life of Tc-99m is 6.0 hours.

Answer:

Step 1: Determine the number of half-lives that pass during the journey

  • The journey is 12 hours long

  • Two half-lives pass over the course of the journey

Step 2: Determine the initial mass of Tc-99m

  • Mass has halved twice to reach 1 kg

  • Initial mass was 4 kg

Step 3: Determine the percentage of Tc-99m lost

  • 3 kg of Tc-99m was lost

  • This is 75% of the initial mass

Examiner Tips and Tricks

You don't need to know the ins-and-outs of the molybdenum-technetium generator, but expect to come across questions regarding the half-lives of each radioisotope and why the generator is required.

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Dan Mitchell-Garnett

Author: Dan Mitchell-Garnett

Expertise: Physics Content Creator

Dan graduated with a First-class Masters degree in Physics at Durham University, specialising in cell membrane biophysics. After being awarded an Institute of Physics Teacher Training Scholarship, Dan taught physics in secondary schools in the North of England before moving to Save My Exams. Here, he carries on his passion for writing challenging physics questions and helping young people learn to love physics.