Organic Synthesis (AQA A Level Chemistry): Exam Questions

The following reaction sequence is missing two intermediates:

3 carbon alkene     →     K     →     L    →      4 carbon amine

What are the missing intermediate compounds, K and L?

Tartaric acid can occur naturally, for example in wine, and may be synthesised in the laboratory.

The laboratory synthesis occurs in 2 steps:

Which reagents could be used for this synthesis?

What is the type of reaction taking place in each step?

Propanone can be turned into 2-bromopropane in a three step synthesis via two intermediates:

                            Step 1                          Step 2                    Step 3    

propanone       →       propan-2-ol     →       propene      →       2-bromopropane

 The reagents for each step could be:

Butylamine can be prepared in two steps from 1-bromopropane

CH₃CH₂CH₂Br  →    X    → CH₃CH₂CH₂CH₂NH₂

What is the structural formula of X?

Propyl 4-aminobenzoate or risocaine is a local anesthetic that can be synthesised from 4-nitrobenzaldehyde via the following three step synthesis.

Which row contains the correct molecular formulae of compounds X and Y?

Methyl 2-methyl propenoate can be synthesised from propanone via the following four step synthesis.

Which type of reaction is involved in each of the steps?

Mesalazine, C₇H₇NO₃, can be synthesised from salicylic acid, C₇H₆O₃, in a two step synthesis.

Which row shows the correct reagents for two steps involved in the synthesis of mesalazine?

Which row contains the correct number of minimum steps to convert an aldehyde into the given compound?

1-chloropropane can be used to produce an amine via two different synthetic routes, direct and indirect.

Which pair of statements about the direct route and the indirect route is not correct?