Batch & Continuous Fermentation (OCR A Level Biology): Revision Note

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Batch & Continuous Fermentation

  • Microorganisms can be grown under controlled conditions in larger fermenters

  • The product of fermentation is either the microorganisms itself e.g. mycoprotein, or a product produced by the microorganism e.g. insulin

  • There are two main methods used to culture microorganisms by fermentation:

    • Batch fermentation

      • Microorganisms are grown in batches in the fermentation vessel

      • Once the culture cycle is complete, the product is removed, the fermenter is cleaned and a new batch of microorganisms is grown

      • This is known as a closed culture

    • Continuous fermentation

      • Microorganisms are continually grown and the products harvested

      • Nutrients are added and waste is removed throughout the culturing process

Maintaining optimum conditions in the fermenter

  • In order to maximise growth and productivity of the microorganisms, the fermenter must be carefully monitored and controlled to ensure conditions are optimum

Optimum Conditions for Fermentation Table

Table outlining factors like pH, temperature, oxygen availability, nutrient supply, agitation, contamination, and waste removal to optimise microorganism productivity.
Industrial fermenter, IGCSE & GCSE Biology revision notes

A fermenter is carefully monitored and controlled to ensure optimum conditions for growth of microorganisms. This will maximise yield of the required product

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