The Four Stages in Aerobic Respiration (OCR A Level Biology): Revision Note

Lára Marie McIvor

Last updated

The Four Stages in Aerobic Respiration

Where does aerobic respiration occur?

  • Glucose is the main respiratory substrate used by cells

  • Aerobic respiration is the process of breaking down a respiratory substrate in order to produce ATP using oxygen

  • The process of aerobic respiration using glucose can be split into four stages

  • Each stage occurs at a particular location in a eukaryotic cell:

    • Glycolysis takes place in the cell cytoplasm

    • The Link reaction takes place in the matrix of the mitochondria

    • The Krebs cycle takes place in the matrix of the mitochondria

    • Oxidative phosphorylation occurs at the inner membrane of the mitochondria

Four Stages of Respiration Table

 Stage

 Description

 Location

 1. Glycolysis

Phosphorylation and splitting of glucose

 Cell cytoplasm

 2. Link reaction

Decarboxylation and dehydrogenation of pyruvate

 Matrix of mitochondria

 3. Krebs cycle

Cyclical pathway with enzyme-controlled reactions

 Matrix of mitochondria

 4. Oxidative phosphorylation

Production of ATP through oxidation of hydrogen atoms

 Inner membrane of mitochondria

Examiner Tips and Tricks

It’s important to know the exact locations of each stage. It is not enough to say the Krebs cycle takes place in the mitochondria, you need to say it takes place in the matrix of the mitochondria.

You've read 0 of your 5 free revision notes this week

Sign up now. It’s free!

Join the 100,000+ Students that ❤️ Save My Exams

the (exam) results speak for themselves:

Did this page help you?

Lára Marie McIvor

Author: Lára Marie McIvor

Expertise: Biology Lead

Lára graduated from Oxford University in Biological Sciences and has now been a science tutor working in the UK for several years. Lára has a particular interest in the area of infectious disease and epidemiology, and enjoys creating original educational materials that develop confidence and facilitate learning.