Generator Potential (AQA A Level Biology)

Revision Note

Lára Marie McIvor

Written by: Lára Marie McIvor

Reviewed by: Lucy Kirkham

Establishment of a Generator Potential

  • When Pacinian corpuscles are stimulated by pressure on the skin this leads to the establishment of a generator potential

    • This happens due to the movement of charged ions across the membrane

  • There is usually an excess of positively charged sodium ions (Na+) surrounding the axon

  • When pressure is exerted on the Pacinian corpuscle the layers of membrane become distorted and the stretch-mediated sodium protein channels in the axon membrane open

    • These channels are referred to as stretch-mediated sodium channels

  • Sodium ions enter the axon via facilitated diffusion

  • This influx of ions changes the electrical potential difference across the membrane

    • This leads to depolarisation

    • This establishes a generator potential

  • The generator potential triggers impulses (action potentials) that travel along the sensory neurone to the central nervous system

Generator potential 1, downloadable AS & A Level Biology revision notes
Generator potential 2, downloadable AS & A Level Biology revision notes

The influx of sodium ions establishes an electrical potential difference across the membrane of the axon. This is the generator potential.

Examiner Tips and Tricks

In the following sentence, the words in speech marks are the underlined keywords found in mark schemes - these must be incorporated to achieve the marks:

Pressure causes the "stretch-mediated" sodium ion channels to "deform", causing sodium "ions" to flow into the axon. This causes "depolarisation" which leads to a generator potential.

Use our topic questions to ensure that you are hitting the keywords in your answers!

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Lára Marie McIvor

Author: Lára Marie McIvor

Expertise: Biology Lead

Lára graduated from Oxford University in Biological Sciences and has now been a science tutor working in the UK for several years. Lára has a particular interest in the area of infectious disease and epidemiology, and enjoys creating original educational materials that develop confidence and facilitate learning.

Lucy Kirkham

Author: Lucy Kirkham

Expertise: Head of STEM

Lucy has been a passionate Maths teacher for over 12 years, teaching maths across the UK and abroad helping to engage, interest and develop confidence in the subject at all levels.Working as a Head of Department and then Director of Maths, Lucy has advised schools and academy trusts in both Scotland and the East Midlands, where her role was to support and coach teachers to improve Maths teaching for all.