The Pacinian Corpuscle (AQA A Level Biology): Revision Note
Exam code: 7402
Receptors: Pacinian corpuscles
Receptors are cells that detect stimuli; they are specific, meaning that each type of receptor detects a different type of stimulus
E.g. the skin contains touch receptors that are sensitive to:
light pressure
deep pressure
sustained pressure
temperature
pain
Pacinian corpuscles are a type of receptor found deep in the skin; they respond to changes in pressure
When Pacinian corpuscles are stimulated by pressure it leads to an initial change in the potential difference across the cell surface membrane; this is a generator potential

Examiner Tips and Tricks
Don’t confuse Pacinian corpuscles with other types of receptor; remember that all receptors are specific, and so they will differ in structure and location.
Pacinian corpuscle structure
Pacinian corpuscles are found at the sensory neurone endings
They are made of many layers of membrane that are separated by gel
The membrane layers are sometimes referred to as:
connective tissue
lamellae

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