The Pacinian Corpuscle (AQA A Level Biology): Revision Note

Exam code: 7402

Lára Marie McIvor

Written by: Lára Marie McIvor

Reviewed by: Naomi Holyoak

Updated on

Receptors: Pacinian corpuscles

  • Receptors are cells that detect stimuli; they are specific, meaning that each type of receptor detects a different type of stimulus

    • E.g. the skin contains touch receptors that are sensitive to:

      • light pressure

      • deep pressure

      • sustained pressure

      • temperature

      • pain

  • Pacinian corpuscles are a type of receptor found deep in the skin; they respond to changes in pressure

  • When Pacinian corpuscles are stimulated by pressure it leads to an initial change in the potential difference across the cell surface membrane; this is a generator potential

Cross-section of skin showing epidermal, dermal, and fatty layers with hair follicle, muscles, and various receptors for touch, pressure, and temperature.
Pacinian corpuscles are a type of receptor cell in the skin that responds specifically to pressure change

Examiner Tips and Tricks

Don’t confuse Pacinian corpuscles with other types of receptor; remember that all receptors are specific, and so they will differ in structure and location.

Pacinian corpuscle structure

  • Pacinian corpuscles are found at the sensory neurone endings

  • They are made of many layers of membrane that are separated by gel

    • The membrane layers are sometimes referred to as:

      • connective tissue

      • lamellae

Cross-section diagram of a Pacinian corpuscle highlighting sensory neurone ending, axon, capsule, layers of connective tissue and a blood capillary.
The ending of the sensory neurone is surrounded by layers of membrane

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Lára Marie McIvor

Author: Lára Marie McIvor

Expertise: Biology, Psychology & Sociology Subject Lead

Lára graduated from Oxford University in Biological Sciences and has now been a science tutor working in the UK for several years. Lára has a particular interest in the area of infectious disease and epidemiology, and enjoys creating original educational materials that develop confidence and facilitate learning.

Naomi Holyoak

Reviewer: Naomi Holyoak

Expertise: Biology Content Creator

Naomi graduated from the University of Oxford with a degree in Biological Sciences. She has 8 years of classroom experience teaching Key Stage 3 up to A-Level biology, and is currently a tutor and A-Level examiner. Naomi especially enjoys creating resources that enable students to build a solid understanding of subject content, while also connecting their knowledge with biology’s exciting, real-world applications.