Prokaryotic DNA (AQA A Level Biology)

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DNA in Prokaryotes

  • The DNA in prokaryotic cells is significantly different from the DNA found in eukaryotic cells
  • “Prokaryote” means “before the nucleus”
  • The DNA is double-stranded
  • Prokaryotes possess a single, circular chromosomal DNA molecule
    • It is sometimes referred to as a nucleoid

  • They also usually have one or more plasmids
    • Plasmids are very small circular DNA molecules
    • They usually only contain a few genes
    • Plasmids are more accessible for proteins required for gene expression and therefore contain genes that are required often, quickly and/or in emergencies
    • The genes for antibiotic resistance are often found in plasmids

  • The DNA within prokaryotic cells is not associated with any proteins
    • Eukaryotic DNA associates with histone proteins

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Image showing the arrangement of DNA within a prokaryotic cell

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Lára

Author: Lára

Expertise: Biology Lead

Lára graduated from Oxford University in Biological Sciences and has now been a science tutor working in the UK for several years. Lára has a particular interest in the area of infectious disease and epidemiology, and enjoys creating original educational materials that develop confidence and facilitate learning.