AIDS (AQA A Level Biology)

Revision Note

Lára Marie McIvor

Written by: Lára Marie McIvor

Reviewed by: Lucy Kirkham

AIDS

Symptoms of AIDS

  • Immediately after infection with HIV people often suffer mild flu-like symptoms

  • These symptoms pass and for a period of time infected people might not know they are infected

  • After several months or years, the viral DNA replicated by the HIV virus particles becomes active

  • They gradually destroy and reduce the number of helper T cells present in a host

  • This is detrimental as helper T cells play an important role in the specific immune response

    • They stimulate B cells, the production of antibodies and increased rates of phagocytosis

  • When an individual can no longer produce antibodies they are said to have advanced acquired immunodeficiency syndrome (AIDS)

  • As they can no longer produce antibodies against pathogens they are immuno-comprised and unable to fight off infections

  • They begin to suffer from diseases that would usually cause very minor issues in healthy individuals

    • These diseases are described as opportunistic

    • Tuberculosis (TB) is a common example

  • It is these opportunistic diseases that cause an individual with advanced AIDS to die

Treatment of AIDS

  • As of yet, there is no cure for AIDS

  • There are many drugs that are very effective at slowing the spread of the virus within the body

  • When provided with adequate medical care individuals with HIV have the same life expectancy as those without the virus

Antibiotics and viruses

  • Antibiotics are commonly used to kill bacteria or limit bacterial growth

  • The mechanism by which they work can vary. Some interfere with the metabolism of bacterial cells while others prevent protein synthesis

  • Antibiotics are ineffective against viruses as they are non-living

  • Viruses are particles and not cells

    • They have no metabolism or cell structure for antibiotics to act on and disrupt

Examiner Tips and Tricks

Try not to confuse the terms HIV and AIDS. Many people often use them interchangeably when they actually mean different things.

  • HIV is a virus

  • AIDS is the disease caused by HIV

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Lára Marie McIvor

Author: Lára Marie McIvor

Expertise: Biology Lead

Lára graduated from Oxford University in Biological Sciences and has now been a science tutor working in the UK for several years. Lára has a particular interest in the area of infectious disease and epidemiology, and enjoys creating original educational materials that develop confidence and facilitate learning.

Lucy Kirkham

Author: Lucy Kirkham

Expertise: Head of STEM

Lucy has been a passionate Maths teacher for over 12 years, teaching maths across the UK and abroad helping to engage, interest and develop confidence in the subject at all levels.Working as a Head of Department and then Director of Maths, Lucy has advised schools and academy trusts in both Scotland and the East Midlands, where her role was to support and coach teachers to improve Maths teaching for all.