Binary Fission (AQA A Level Biology)
Revision Note
Written by: Lára Marie McIvor
Reviewed by: Lucy Kirkham
Binary Fission of Prokaryotic Cells
The process of cell division (binary fission) in prokaryotic cells is much simpler than mitosis in eukaryotic cells
Prokaryotic cells do not possess:
A nucleus
Chromosomes
Membrane-bound organelles
Spindle fibres
They have a single, circular DNA molecule and plasmids
Plasmids are smaller, circular DNA molecules that are also replicated and inherited
The number of copies of plasmids that each cell inherits can vary, although this number is regulated
The process of binary fission
Binary fission is substantially different from mitosis as there is no nuclear envelope to breakdown and there are no spindle fibres present
The process:
The single, circular DNA molecule undergoes DNA replication
Any plasmids present undergo DNA replication
The parent cell divides into two cells, with the cytoplasm roughly halved between the two daughter cells
The two daughter cells each contain a single copy of the circular DNA molecule and a variable number of plasmids
There are mechanisms to ensure that all daughter cells inherit a copy of the single, circular DNA molecule along with some plasmids
If a daughter cell does not receive the single circular DNA molecule or at least one copy of a plasmid they die
The process of binary fission producing genetically identical daughter cells
Examiner Tips and Tricks
The daughter cells produced by binary fission can have a different number of plasmid copies but they are still genetically identical! This is because they still contain the same genetic code (DNA base sequences) they just have more or less identical copies of that code.
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