Binary Fission (AQA A Level Biology): Revision Note
Exam code: 7402
Binary fission of prokaryotic cells
- Cell division in prokaryotes is called binary fission 
- It is simpler than mitosis as cells have no nucleus, chromosomes, spindle fibres, or membrane-bound organelles 
- Prokaryotes only need to replicate - a single, circular DNA molecule 
- plasmids: small, circular DNA molecules 
 
The process of binary fission
- The circular DNA molecule is replicated 
- Plasmids replicate 
- The cytoplasm divides (roughly) equally between daughter cells 
- Each daughter cell is genetically identical and receives - one copy of circular DNA 
- a variable number of plasmids 
 
- There are mechanisms to ensure that all daughter cells inherit a copy of the single, circular DNA molecule along with some plasmids - If a daughter cell does not receive the single circular DNA molecule or at least one copy of a plasmid, it dies 
 

Examiner Tips and Tricks
Binary fission can be a rapid process. Bacteria can divide every 20 minutes under ideal conditions. This rapid reproduction allows them to:
- Colonise new environments quickly 
- Outcompete other microbes 
- Accumulate mutations faster, increasing genetic variation (contributing to the issues surrounding antibiotic resistance) 
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